The school will cover different topics in protein and RNA design as listed below, and will focus on teaching modern modelling approaches in this domain, from statistical physics, computer science, and machine learning fields to recent experimental approaches. Main lectures will consist of 2 mornings of about 3 hours each, followed by afternoon seminars in the same domain and student projects.

The main topics are:

• Protein and RNA Design

Invited speakers :

Daniel Amor, Ecole Normale Supérieure, Paris

Aurore Loisy, IRPHE, Marseille

Francesco Mori, University of Oxford, Oxford

Emma Hodcroft, University of Basel, Basel

Lunch, coffee breaks and a closing cocktail are also included.

Adherent cells in vivo reside on extracellular matrices (ECMs) that possess a topographical organization at different scales. Various types of engineered microstructured substrates have been developed to study the impact of basal topographical cues on cell behavior in vitro. Amongst them, microgrooves mimicking the anisotropic organization of the ECM have been shown to align and elongate different cell types.

09:30-10:00 Martin Weigt Combining phylogeny and coevolution for inferring interactions among paralogous proteins

10:00-10:30 Mingfeng Qiu Self-organization and active mechanics in development

10:30-11:00 Xiaowen Chen Inferring collective dynamics of social mice

11:00-11:30 Coffee break

11:30-12:00 Silvia De Monte To cheat or not to cheat: in this a dilemma?

Ce séminaire interdisciplinaire propose une approche croisée des « humanités médicales » autour de savoirs et de représentations liées au corps, à la maladie et au soin.