Summer school - Molecular Evolution and Design: from Computational Models to Biological and Medical Applications (Cargèse, Corsica)

The school will cover different topics in protein and RNA design as listed below, and will focus on teaching modern modelling approaches in this domain, from statistical physics, computer science, and machine learning fields to recent experimental approaches. Main lectures will consist of 2 mornings of about 3 hours each, followed by afternoon seminars in the same domain and student projects.

The main topics are:

• Protein and RNA Design

• Design of small molecules and medical applications: aptamers, regulatory RNA,..

• Design through in Vitro Evolution: Selex and Directed Evolution

• Design for Immunology

Techniques: Statistical Physics, Machine Learning, Bioinformatics, experimental techniques related to gene synthesis, screening, mutagenesis and experimental evolution.