Aleksandra WALCZAK

biophysics, evolution, immunologie, development, collective behaviour
Department of Physics
, updated on
23 November 2021
Laboratoire de physique de l’ENS (LPENS)
3ème étage, bureau GH307
24, rue Lhomond 75231 Paris cedex 05
01 44 322595

I am a biophysicist interest in many aspects of living systems, from the immune system to development. I work both on direct modeling approaches and data driven analysis of living systems.

Field of research

The precision and reproducibility of biological processes amazes us yet poses a challenge to our understanding of the physical principles that control the emergent properties of biological systems. My research in the field of theoretical biophysics focuses on describing and understanding the behaviour of such strongly interacting, stochastic, nonlinear biological systems. The elements of these systems interact to result in properties which are qualitatively different than the characteristics of their composing subsystems. My recent research focusses on data driven approaches to learn about the effective designs used in immune receptors, bird flocks, development and proteins, as well statistical modeling of gene regulation and immune receptors.


  • T. Dupic, M. Bensouda Koraichi, A. A. Minervina, M. V. Pogorelyy, T. Mora*, A. M. Walczak*, Immune fingerprinting, (2021) PloS Genetics
  • G.Altan-Bonnet, T.Mora, A.M.Walczak, Quantitative Immunology for Physicists, Physics Reports (2020).
  • Q. Marcou, T. Mora, A. M. Walczak, ”IGoR : a tool for high-throughput immune repertoire analysis”, Nature Communications 2018
  • A. Mayer, V. Balasubramanian, T. Mora, A. M. Walczak, ”How a well-adapted immune system is organized”, PNAS (912), 5950 (2015)
  • T. Mora, A. M. Walczak, L. Del Castello, F. Ginelli, S. Melillo, L. Parisi, M. Viale, A. Cavagna and I. Giardina, ”Questioning the activity of active matter in natural flocks of birds”, Nature Physics (2016)
  • . M. Laessig, V. Mustonen and A. M. Walczak, ”Predicting evolution”, Nature Ecology & Evolution 1 (2017)
  • J. Desponds, M. Vergassola, A. M. Walczak, A mechanism for hunchback promoters to readout morphogenetic positional information in less than a minute, eLife (2020)